A Gram-negative core-antigen Vaccine for Ruminant Mastitis
1. Exposure to core antigens provides strong protection:
The lipopolysaccharide of Escherichia coli J5 strain lacks the peripheral O chain, exposing the core antigen, while vaccination with inactivated sheep E. coli vaccine (ruminant animals) can provide protection against endotoxin storm and bacteremia caused by Gram negative bacteria.
2. Reduce the incidence rate of mastitis and relieve clinical symptoms:
The incidence rate of mastitis 90 days before lactation can be significantly reduced by inoculating the vaccine in the dry milk period and early lactation of dairy goats (ruminants), and the severity of clinical symptoms of mastitis can be alleviated after vaccination.
3. Improve milk quality and increase milk production:
After vaccination, the number of somatic cells in the milk sample significantly improved, increasing the milk production of dairy goats (ruminants) and achieving the effect of cost reduction and efficiency enhancement.
4. Reduce treatment duration and decrease elimination rate:
After vaccination, the treatment duration for mastitis is reduced and the elimination rate of dairy goats (ruminants) caused by mastitis is lowered. Ranch can implement selective treatment based on the type of bacteria that cause mastitis



